ab 2315387 Search Results


98
Developmental Studies Hybridoma Bank anti synaptic vesicle protein
Anti Synaptic Vesicle Protein, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Danaher Inc dhsb rrid ab 2315387 rat anti brdu
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Developmental Studies Hybridoma Bank anti synaptic vesicle protein 2
Anti Synaptic Vesicle Protein 2, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Developmental Studies Hybridoma Bank anti-sv2a
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Developmental Studies Hybridoma Bank anti 2h3 primary antibodies
(A) Analysis of RET-positive neurons in the lumbar spinal cord (n=3 animals per group, 6 sections per animal) reveals no difference between the genotypes (B-C) Analyses of NMJs at 35 weeks of age showed significantly more occupied (p=0.0033) NMJs in Gdnf wt/hyper mice and less denervated (p=0.0036) NMJs compared to the Gdnf wt/wt animals (n=5 neurofilament <t>(2H3)</t> and synaptic vesicles (SV2) were stained to visualize the axons and pre-synaptic nerve terminals, α-bungarotoxin (α-BTX) was used to visualize the endplate (stains acetylcholine receptors in skeletal muscle fibers). ( Gdnf wt/wt n=5 and n=6 Gdnf wt/hyper ). (D) Representative images of an NMJ in a 35-week-old Gdnf wt/wt and Gdnf wt/hyper mouse in SOD1 G93A background (scale bar = 10µm). Note the lack of neuronal staining in Gdnf wt/wt in SOD1 G93A background, indicating degeneration of MN axons.
Anti 2h3 Primary Antibodies, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Thermo Fisher alexa fluor 594 goat anti-mouse
(A) Analysis of RET-positive neurons in the lumbar spinal cord (n=3 animals per group, 6 sections per animal) reveals no difference between the genotypes (B-C) Analyses of NMJs at 35 weeks of age showed significantly more occupied (p=0.0033) NMJs in Gdnf wt/hyper mice and less denervated (p=0.0036) NMJs compared to the Gdnf wt/wt animals (n=5 neurofilament <t>(2H3)</t> and synaptic vesicles (SV2) were stained to visualize the axons and pre-synaptic nerve terminals, α-bungarotoxin (α-BTX) was used to visualize the endplate (stains acetylcholine receptors in skeletal muscle fibers). ( Gdnf wt/wt n=5 and n=6 Gdnf wt/hyper ). (D) Representative images of an NMJ in a 35-week-old Gdnf wt/wt and Gdnf wt/hyper mouse in SOD1 G93A background (scale bar = 10µm). Note the lack of neuronal staining in Gdnf wt/wt in SOD1 G93A background, indicating degeneration of MN axons.
Alexa Fluor 594 Goat Anti Mouse, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Developmental Studies Hybridoma Bank mouse monoclonal antibody
(A) Analysis of RET-positive neurons in the lumbar spinal cord (n=3 animals per group, 6 sections per animal) reveals no difference between the genotypes (B-C) Analyses of NMJs at 35 weeks of age showed significantly more occupied (p=0.0033) NMJs in Gdnf wt/hyper mice and less denervated (p=0.0036) NMJs compared to the Gdnf wt/wt animals (n=5 neurofilament <t>(2H3)</t> and synaptic vesicles (SV2) were stained to visualize the axons and pre-synaptic nerve terminals, α-bungarotoxin (α-BTX) was used to visualize the endplate (stains acetylcholine receptors in skeletal muscle fibers). ( Gdnf wt/wt n=5 and n=6 Gdnf wt/hyper ). (D) Representative images of an NMJ in a 35-week-old Gdnf wt/wt and Gdnf wt/hyper mouse in SOD1 G93A background (scale bar = 10µm). Note the lack of neuronal staining in Gdnf wt/wt in SOD1 G93A background, indicating degeneration of MN axons.
Mouse Monoclonal Antibody, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


(A) Analysis of RET-positive neurons in the lumbar spinal cord (n=3 animals per group, 6 sections per animal) reveals no difference between the genotypes (B-C) Analyses of NMJs at 35 weeks of age showed significantly more occupied (p=0.0033) NMJs in Gdnf wt/hyper mice and less denervated (p=0.0036) NMJs compared to the Gdnf wt/wt animals (n=5 neurofilament (2H3) and synaptic vesicles (SV2) were stained to visualize the axons and pre-synaptic nerve terminals, α-bungarotoxin (α-BTX) was used to visualize the endplate (stains acetylcholine receptors in skeletal muscle fibers). ( Gdnf wt/wt n=5 and n=6 Gdnf wt/hyper ). (D) Representative images of an NMJ in a 35-week-old Gdnf wt/wt and Gdnf wt/hyper mouse in SOD1 G93A background (scale bar = 10µm). Note the lack of neuronal staining in Gdnf wt/wt in SOD1 G93A background, indicating degeneration of MN axons.

Journal: medRxiv

Article Title: GDNF levels regulate lumbar motor neuron physiology and determine life expectancy in limb-onset ALS

doi: 10.64898/2025.12.05.25341683

Figure Lengend Snippet: (A) Analysis of RET-positive neurons in the lumbar spinal cord (n=3 animals per group, 6 sections per animal) reveals no difference between the genotypes (B-C) Analyses of NMJs at 35 weeks of age showed significantly more occupied (p=0.0033) NMJs in Gdnf wt/hyper mice and less denervated (p=0.0036) NMJs compared to the Gdnf wt/wt animals (n=5 neurofilament (2H3) and synaptic vesicles (SV2) were stained to visualize the axons and pre-synaptic nerve terminals, α-bungarotoxin (α-BTX) was used to visualize the endplate (stains acetylcholine receptors in skeletal muscle fibers). ( Gdnf wt/wt n=5 and n=6 Gdnf wt/hyper ). (D) Representative images of an NMJ in a 35-week-old Gdnf wt/wt and Gdnf wt/hyper mouse in SOD1 G93A background (scale bar = 10µm). Note the lack of neuronal staining in Gdnf wt/wt in SOD1 G93A background, indicating degeneration of MN axons.

Article Snippet: Muscle sections were blocked with PBS-Triton X-100 (0.5%) and incubated for 24h with anti-SV2 and anti-2H3 primary antibodies (1:100, DSHB, AB_2315387, and AB_531793), recognizing neurofilament (2H3) and synaptic vesicles (SV2) to visualize the axons and pre-synaptic nerve terminals.

Techniques: Staining